Tissue Repair Research

TB-500

Thymosin β4 fragment

Also known as Thymosin beta-4 (17–23) fragment, Tβ4 fragment.

A synthetic peptide corresponding to the actin-binding region of thymosin beta-4, studied in cell-migration, angiogenesis and wound-model research.

Current lot: SN-TB5-2608
Purity: 99.48% by HPLC
Tested: Aug 11, 2026
Stocked in: United States, Canada, Australia

Synamino Sciences research vial with a silver cap on a slate-blue background

Ships from

Vial size

$36.00

USD · 5 mg · In stock

Qty

Order by 2:00 PM PT for same-day dispatch from Reno, Nevada. 1–3 business days by USPS Priority and UPS. Free shipping over $150.00.

For laboratory research use only. Not for human or veterinary use.

About the compound

TB-500 reproduces the LKKTETQ actin-binding motif of thymosin beta-4, a 43-residue protein present in most cell types. Research on the fragment and its parent protein focuses on actin sequestration, cell motility and tissue-repair models.

Supplied as a lyophilized powder in 5 mg and 10 mg vials.

Studied inActin dynamics · Cell migration · Angiogenesis · Wound models

Certificate of analysis

The certificate for the lot currently shipping. Every vial in that lot carries the same lot number on its label.

Certificate of analysis

TB-500 · 10 mg

Lot SN-TB5-2608 · tested Aug 11, 2026

99.48%

Purity by HPLC

Labeled: 10 mg
Measured: 10.3 mg
Panel: 6 passed · 2 reported
Laboratory: Independent ISO/IEC 17025 accredited laboratory

Assay	Method	Result	Outcome
Appearance	Visual	White lyophilized powder	Pass
Purity	HPLC · spec ≥ 98%	99.48%	Pass
Net peptide content	HPLC	10.3 mg	Reported
Identity	LC-MS	Confirmed	Pass
Heavy metals	ICP-MS	Not detected	Pass
Sterility	USP <71>	No growth	Pass
Endotoxin	LAL · USP <85>	< 0.05 EU/mL	Reported
Residual solvents	GC-HS	Within limits	Pass

Specification and storage

CAS number: 885340-08-9
Molecular formula: C38H68N10O14
Molecular weight: 889.0 g/mol
Residues: 7
Sequence: Ac-LKKTETQ-OH
Reference record: PubChem entry

Storage

Sealed lyophilized vials are stable at room temperature for short periods; store at 2–8 °C for routine use.
For long-term storage keep sealed vials at −20 °C, protected from light and moisture.
Reconstituted solutions should be refrigerated at 2–8 °C and used within the period defined by your laboratory's protocol.

Literature

Peer-reviewed publications on this compound. Provided for reference; they are not claims about this product.

01
FASEB Journal · 2003
The actin binding site on thymosin beta4 promotes angiogenesis
Philp D, Huff T, Gho YS, et al.
02
FASEB Journal · 2010
Biological activities of thymosin beta4 defined by active sites in short peptide sequences
Sosne G, Qiu P, Goldstein AL, et al.
03
The EMBO Journal · 1996
The actin binding site of thymosin beta 4 mapped by mutational analysis
Van Troys M, Dewitte D, Goethals M, et al.

Studied alongside

BPC-157
Pentadecapeptide
from $32.00
Wolverine Blend
BPC-157 · TB-500
from $69.00
GHK-Cu
Copper tripeptide
from $34.00

Research notice

TB-500 is supplied for in vitro laboratory research and analytical use by qualified professionals. It is not a medicine, supplement or cosmetic, has not been evaluated by any regulator, and is not for human or veterinary use. Published findings cited on this page are provided for reference and are not claims about this product.