Cellular & Immune Research

Humanin

Mitochondrial-derived peptide

Also known as HN, MT-RNR2-derived peptide.

A 24-residue peptide encoded within the mitochondrial 16S rRNA gene, studied in cytoprotection, neuronal-survival and metabolic-stress models.

Current lot: SN-HUM-2607
Purity: 99.09% by HPLC
Tested: Jul 31, 2026
Stocked in: United States

Synamino Sciences research vial with a silver cap on a teal background

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Vial size

$59.00

USD · 10 mg · In stock

Qty

Order by 2:00 PM PT for same-day dispatch from Reno, Nevada. 1–3 business days by USPS Priority and UPS. Free shipping over $150.00.

For laboratory research use only. Not for human or veterinary use.

About the compound

Humanin was the first mitochondrial-derived peptide to be described. It is investigated for its interactions with pro-apoptotic proteins and cell-surface receptors in neuronal and metabolic cell models.

Supplied as a lyophilized powder.

Studied inCytoprotection · Neuronal survival · Mitochondrial signalling

Certificate of analysis

The certificate for the lot currently shipping. Every vial in that lot carries the same lot number on its label.

Certificate of analysis

Humanin · 10 mg

Lot SN-HUM-2607 · tested Jul 31, 2026

99.09%

Purity by HPLC

Labeled: 10 mg
Measured: 10.1 mg
Panel: 6 passed · 2 reported
Laboratory: Independent ISO/IEC 17025 accredited laboratory

Assay	Method	Result	Outcome
Appearance	Visual	White lyophilized powder	Pass
Purity	HPLC · spec ≥ 98%	99.09%	Pass
Net peptide content	HPLC	10.1 mg	Reported
Identity	LC-MS	Confirmed	Pass
Heavy metals	ICP-MS	Not detected	Pass
Sterility	USP <71>	No growth	Pass
Endotoxin	LAL · USP <85>	< 0.05 EU/mL	Reported
Residual solvents	GC-HS	Within limits	Pass

Specification and storage

CAS number: 330936-69-1
Molecular formula: C119H204N34O32S2
Molecular weight: 2687.2 g/mol
Residues: 24
Sequence: MAPRGFSCLLLLTSEIDLPVKRRA
Reference record: PubChem entry

Storage

Sealed lyophilized vials are stable at room temperature for short periods; store at 2–8 °C for routine use.
For long-term storage keep sealed vials at −20 °C, protected from light and moisture.
Reconstituted solutions should be refrigerated at 2–8 °C and used within the period defined by your laboratory's protocol.

Literature

Peer-reviewed publications on this compound. Provided for reference; they are not claims about this product.

01
Current Medicinal Chemistry · 2011
Advances in characterization of neuroprotective peptide, humanin
Arakawa T, Hirano A, Shiraki K, et al.
02
Neuroscience Letters · 2002
Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults
Tajima H, Niikura T, Hashimoto Y, et al.
03
Brain Research · 2008
Neuroprotective effect of humanin on cerebral ischemia/reperfusion injury is mediated by a PI3K/Akt pathway
Xu X, Chua CC, Gao J, et al.

Studied alongside

MOTS-c
Mitochondrial-derived peptide
from $42.00
SS-31
Elamipretide · mitochondria-targeting tetrapeptide
from $79.00

Research notice

Humanin is supplied for in vitro laboratory research and analytical use by qualified professionals. It is not a medicine, supplement or cosmetic, has not been evaluated by any regulator, and is not for human or veterinary use. Published findings cited on this page are provided for reference and are not claims about this product.